Summary: Mass spectrometry (MS)-based Tote Bag untargeted metabolomic and lipidomic approaches are being used increasingly in biomedical research.The adoption and integration of these data are critical to the overall multi-omic toolkit.Recently, a sample extraction method called Multi-ABLE has been developed, which enables concurrent generation of

With critical limb ischemia (CLI) being a multi-factorial disease, it is becoming evident that gene therapy with a multiple bio-functional growth factor could achieve better therapeutic outcomes.Cytochrome P450 epoxygenase-2J2 (CYP2J2) and its catalytic products epoxyeicosatrienoic acids (EETs) exhibit pleiotropic biological activities, including p

Syndecan-1 is a transmembrane heparan sulfate-bearing proteoglycan known to regulate multiple biological functions at the cell surface and within the extracellular matrix.Its functional activity can be modulated by heparanase, an enzyme that cleaves heparan sulfate chains and whose expression has been associated with an aggressive phenotype Interio